Knocking the Wnt out of the sails of leukemia stem cell development.

نویسندگان

  • Aniruddha J Deshpande
  • Christian Buske
چکیده

Tumor propagation by cancer stem cells (CSCs) requires their ability to self-renew, and yet the signal pathways involved in this process remain poorly defined. In the December issue of Cancer Cell, Zhao et al. (2007) provide compelling evidence that Wnt/beta-catenin signaling is crucial for the maintenance of chronic myelogenous leukemia (CML) stem cells.

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عنوان ژورنال:
  • Cell stem cell

دوره 1 6  شماره 

صفحات  -

تاریخ انتشار 2007